Second-half goals from Bernardo Silva and Leroy Sane saw City record a comfortable victory over their local rivals and move back to the top of the table, one point clear of Liverpool with three games to play.
“Liverpool I don’t think are going to drop too many points, but it’s in our hands,” Guardiola said.
“Three games, we won the last 11. It’s incredible what these players have done so far, but still we have a job to do.”
But which of his stars performed best at Old Trafford?
Man City Player Ratings
Kyle Walker 7
Vincent Kompany 7
Aymeric Laporte 7
Oleksandr Zinchenko 7
Ilkay Gundogan 8
David Silva 8
Raheem Sterling 7
Sergio Aguero 7
Bernardo Silva 9 MOTM
Leroy Sane 7 (Gundogan, 51)
Gabriel Jesus (Aguero, 88)
Danilo (Gundogan, 88)
Guardiola said: “If that victory happened in November, December or January we would celebrate it more, enjoy it more. Maybe tonight we can enjoy it, but tomorrow it’s over, it’s gone, so you have to be focused, so focused.”
There is no let-up for City, who travel to Burnley on Sunday with every game a must-win.
“I know the people are going to talk about how beautiful we are, how handsome we are, like this, like that, but now we have to go to Burnley,” Guardiola added.
“In my two previous seasons going to Burnley was incredibly tough, so we have to be focused, because Burnley is always a tough, tough game to play.”
Man City remaining fixtures
April 28 – Burnley (A)
May 6 – Leicester (H)
May 12 – Brighton (A)
May 18 – Watford (FA Cup final)