United have a real chance of winning the FA Cup under Ole Gunnar Solskjaer this season.
They have already claimed the scalps of Chelsea and Arsenal in previous rounds.
But their latest opponent presents a very different danger – with Wolves being the surprise package this season.
Nuno Espirito Santo’s men came up from the Championship last season but find themselves on the peripherals of European football next season after a fine year in the Premier League.
They are seventh in the table and have taken points off the likes of Manchester City, Chelsea and Arsenal.
Wolves also knocked Liverpool out of the cup earlier this year, courtesy of a Ruben Neves wonder strike.
And Matic has told his team-mate to be wary of the threat the Molineux outfit pose.
“We know that Wolves are a great team,” Matic told ESPN FC.
“This season they have played great football and had some good results.
“They have good players — some of them I know because I played against them in the Portuguese league.
“We will have a very difficult test for us and we will be ready. They have some top class players like [Joao] Moutinho.
“I know him very well from Porto. For me, one of the best midfielders in the Premier League. Their results aren’t surprising because I know them well.”
Arsenal ended Solskjaer’s unbeaten start to life in the Premier League after beating them 2-0 last week but Matic has been able to pick himself back up again since then.
He added: “Every team has quality and we cannot win all the time.
“Of course we are not happy with the game that we lost but we know that we did some great things — and Saturday against Wolves is a great opportunity to bounce back.”