In the game of the round, United travel to the Emirates to take on their old rivals in the FA Cup.
With both sides neck and neck in the Premier League, a place in the next round may not be the only thing up for grabs.
The Gunners are battling to find themselves back in the top four and are three points behind Chelsea.
But Solskjaer has revitalised a dead and buried United side that are now also in contention for a Champions League spot.
However, the Norwegian will not have a full squad available to him tomorrow night, with the manager revealing three players will definitely miss out.
“It’s still those three [Marouane Fellaini, Marcos Rojo, Chris Smalling] who are missing,” he told MUTV.
“Smalling has started training so hopefully he’ll be available maybe next week, so it’s looking good for him. Fellaini and Rojo are still a bit away.”
Rojo is still ruled out with a knee problem, Fellaini has a calf injury while Smalling has a damaged foot.
The FA Cup presents Solskjaer with the strongest chance of winning silverware in his short time at the club.
The United legend has a contract until the end of the season but has already indicated he would like to stay longer.
And he has the support of the fans, who are falling back in love with the Red Devils after a gloomy few months under Jose Mourinho.
Meanwhile, one player that has been linked with a move away is Eric Bailly.
The Ivorian has courted the attention of Arsenal, who made an enquiry for the centre-back as a result of being desperate short of quality at the back.
Solskjaer insisted that any interest in the former Villarreal star does not surprise him, despite him being out of the squad recently.
“I’m not surprised if they do [want him], to put it that way,” he added.
“But that’s just one of those things there’s always speculation, it’s not a big surprise.