United kept up their pre-season momentum by romping to a 4-0 win over Leeds just days after beating Perth Glory 2-0.
Antonio Conte’s Inter side will be a much tougher test in the Singapore National Stadium however.
United boss Ole Gunnar Solskjaer has made six changes to the side who beat Leeds three days ago.
Starsport predicts three key talking points that could emerge from today’s encounter.
Man Utd 1-0 Inter Milan – AS IT HAPPENED
– Dan James screws shot wide after 35 mins with United much the better side.
– Jesse Lingard has a shot cleared off the line before Nemanja Matick hits the post with a free header.
– Mason Greenwood, 17, scores with a powerful effort after Ashley Young’s free-kick was palmed away from goal.
Man Utd team: De Gea; Wan-Bissaka, Tuanzebe, Lindelof, Shaw; Pogba, Matic; James, Lingard, Martial; Rashford
Axel Tuanzebe to shine at centre-back
Tuanzebe, 21, has been handed a start by Solskjaer and he will be desperate to impress his manager.
The young defender spent last season on loan at Aston Villa where he showed masses of potential while helping the Villans to Premier League promotion.
Fortunately he will not have to deal with Inter’s star striker Mauro Icardi, who has been left out of the tour to allow him to find a new club.
With a £80m deal for Leicester centre-back Harry Maguire still as yet incomplete, Tuanzebe will feel he has the chance to work his way into United’s first-team squad.
Solskjaer has plans to loan him out again this season, but a big performance against Inter could change the Norwegian’s mind.
Nemanja Matic not captain material
Matic has been given the captain’s armband for today’s game, but surely Manchester United can do better than the Serbian plodder.
His £40m capture from Chelsea two years ago initially seemed like a inspired signing, but not any longer.
Matic’s mobility has never been great, but the 30-year-old’s lack of pace is now a hindrance to the style that United are aiming to utilise.
Solskjaer would be better off backing his own pledge to put his faith in youth by sticking with Scott McTominay in central midfield.
Solskjaer’s attacking tactics to bear fruit
The United boss has picked Anthony Martial, Jesse Lingard and Marcus Rashford to start against the Serie A side today.
Rashford is out to score for the third successive game on the tour and he is likely to play in a central role.
Martial should revert to his familiar left-sided slot, while Lingard who, like Martial, came off the bench in midweek will be eyeing a goal.
Red Devils fans are certainly enjoying their side’s more free-spirited approach to the game after Jose Mourinho stifled the team’s attacking creativity during his tenure.
Solskjaer’s dynamic looking line-up should play to Rashford’s strengths and it wouldn’t be a surprise to see the England man net at least once.