The Saints needed an injury-time penalty to beat the Hammers 3-2 in a pulsating encounter at St Mary’s.
Manchester United’s 4-0 thrashing of Swansea is second on the programme with Stoke’s win over Arsenal up third.
That is followed by Burnley’s home defeat to West Brom with Leicester’s victory over Brighton on fifth.
Watford’s 2-0 win at Bournemouth is the penultimate game with Liverpool’s 1-0 success over Crystal Palace on last.
Manchester United: Team average – 7.71
Match of the Day is on at 10:25pm on BBC One.
Host Gary Linker confirmed the running order on social media, adding: “Much to enjoy.”
While still very early on in the new Premier League season, West Brom fans will enjoy seeing the table this evening.
The Baggies have joined United at the top on six points from their opening two games.
Huddersfield, Manchester City, Tottenham and Everton can all join the top two in the remaining games of the weekend.
Huddersfield host Newcastle tomorrow before champions Chelsea make the short trip to Wembley to face Spurs.
City and Everton then go head-to-head at the Etihad on Monday night.