Alderweireld is under contract until the end of next season after Spurs triggered an extension clause in December but will then be allowed to leave for a cut-price £26million.
This has led to some of Europe’s top clubs declaring their interest but if reports are to be believed, Manchester United are leading the chase.
Barcelona and Juventus are thought to be close behind but it seems that one way or another, the Belgium international will leave.
Since joining Tottenham in 2015 Alderweireld has made more than 100 Premier League appearances, scoring five goals.
He has become one of the best defenders in England and has helped catapult the north London side into Premier League title contention.
The Red Devils have been looking for a top class centre-half for some time after being unable to find a tried and tested partnership in defence.
Spurs fans, who are waiting to see who they will draw in the quarter-final of the Champions League on Friday, have reacted angrily to the club possible letting one of their prize assets leave.
“Such a small club mentality. Selling to direct rivals,” said one fan.
The Twitter reaction comes ahead of:
“Such a small club mentality. Selling to direct rivals”
Another tweeted: “and so it begins…….The heirachy at Spurs showing ZERO ambition and happy to see the dismantling of this squad. Be interesting to see if they increase ST prices next Monday. If they do then im done with football.”
“shocking – should do everything they can to keep him and def not sell to a rival,” said another Spurs fan.
Another angry Twitter user said: “Selling top players to direct rivals really sticks in the throat. They won’t be rivals for long if we keep doing it.”
“Toby has shown great passion this season, is playing regularly, hopefully we can put a deal together for for him, such a key player #THFC,” said another.
Meanwhile, former Spurs and Manchester United forward Dimitar Berbatov has given his prediction ahead of the Champions League draw.
Both teams could potentially draw each other with their being no protection for clubs from the same country any more.
“No-one’s going to dare write United off anymore are they?” he told Betfair.
“As the saying goes, ‘Respect the giant, otherwise you’ll suffer’.
“Their players will have been saying ‘we’ll take anyone next’ in the dressing room on Wednesday.
“And they are proving week after week that they are a match for anyone.
“Both they and Spurs have a chance of winning the Champions League now.