The Red Devils face their rivals this week in their first meeting for almost eight years.
United and Leeds last went head-to-head in the League Cup in September 2011.
Sir Alex Ferguson was in charge of United at the time as they ran out 3-0 winners at Elland Road.
Much has changed at both clubs since then and they are equally active in the transfer market this summer.
At the Yorkshire club, attacking midfielder Helder Costa has been snapped up from Wolves on a loan deal with an obligation to buy.
Winger Jack Harrison has returned to Elland Road on loan from Manchester City following his solid season there.
Jack Clarke was sold to Tottenham for £10m but that saw him head straight back to Leeds on loan until the end of the season.
However, Football Insider say none of the trio will play in the crunch friendly against United, let alone travel Down Under with the rest of the squad.
“Manager Marcelo Bielsa has opted leave the new recruits in Yorkshire”
Ben White, Liam McCarron, Ezgjan Alioski, Mateusz Klich and Jamie Shackletonwill also apparently be left behind.
Manager Marcelo Bielsa has opted leave the new recruits in Yorkshire.
The Argentinian wants the new signings and players who returned late to pre-season to remain in England to work on their fitness.
Leeds have already played two friendlies as part of their busy July schedule.
United are Leeds’ first test in Australia on Wednesday (12pm) and they then face Western Sydney Wanderers next Saturday (10am).
A friendly against Serie A side Cagliari rounds off Leeds’ pre-season schedule on July 27 before they begin their Championship campaign at Bristol City on August 4.
Leeds fans Down Under will be disappointed, though, to see so many of their key players not featuring, especially against United.
Ole Gunnar Solskjaer has taken an almost full-strength squad with him to Australia.