The Greek ace has been heavily linked with a move away from the Serie A outfit and almost completed a switch to the Middle East in January.
But despite staying in Roma beyond the winter window, it appears a host of names are ready to lure the unsettled star away from the Italian side.
According to CalcioMercato, Atletico Madrid, Juventus and ‘all the big English clubs’ are vying for Manolas’ signature.
However, the publication claims United are in ‘first place’ when it comes to a deal.
Manolas has previously stated his interest in both Real Madrid and Barcelona but may be offered a similar wage packet should he move to Old Trafford.
United are desperate for a new central defender and will be pleased to hear Manolas only has a €36m (£30.8m) release clause.
This is significantly cheaper than two of Ed Woodward’s other reported targets – Raphael Varane and Kalidou Koulibaly.
News of the Manolas interest comes as:
The former is said to be unhappy at Madrid and seeking a new challenge.
But Varane would command a world-record fee should he leave the Bernabeu.
Koulibaly is also being valued at around £150m as he continues to attract interest at Napoli.
The Senegal star has been a target of United’s for a while.
Addressing reports about his future this week, Varane told Le Parisien: “I do not want to discuss my future.
“I do not usually express myself publicly about my future.”
United will likely hand Ole Gunnar Solskjaer a war-chest in the summer to rebuild his squad.