Ibrahimovic, who played for United between 2016 and 2018, referred to the Class of ’92 as “the circle of Ferguson”.
He accused them of being over-critical of the club, specifically mentioning their treatment of Paul Pogba.
David Beckham, Paul Scholes, Gary Neville, Phil Neville, Nicky Butt and Giggs make up the Class of ’92.
They played a combined total of 3,450 games during the most successful period in United’s history.
And Giggs responded to Ibrahimovic’s claims ahead of Wales’ upcoming Euro 202 qualifiers.
“Only Nicky [Butt] is connected with the club now,” said the Wales manager.
“But when you play over 2,000 games between us, we are going to have an opinion.
“Sometimes it’s positive, sometimes negative, but it doesn’t have an effect on results.
“We are supporters. That’s what football is about, having different opinions.
“But he [Ibrahimovic] obviously knows more about the club than us.”
Giggs’ comments come amid news of:
Giggs was also asked about the possibility of Manchester City going one further than United’s famous treble-winning 1999.
United won the Champions League, Premier League and FA Cup that year but City remain on course for an unprecedented quadruple.
“I’ve got enough to worry about, please don’t bring that up.” Giggs said. “They’re a fantastic team, aren’t they?
“They’ve already got one and United going out of the FA Cup makes it a little bit easier for them.
“They’ve got a long way to go but just like us in the treble, you need a lot of things to go for you. That bit of luck, which they had at the weekend.
“But they are a brilliant team. It will be interesting to see what they can achieve.”